Unlocking the genetics of mental health disorders affecting young people

posted 3 Mar 2013, 15:40 by Damian Wood   [ updated 3 Mar 2013, 15:40 ]
A seminal paper by the Psychiatric Genomics Consortium published in the Lancet (doi:10.1016/S0140-6736(12)62129-1) demonstrates that four risk loci have significant and overlapping links with five major psychiatric disorders (autism spectrum disorder, ADHD, bipolar disorder, major depressive disorder and schizophrenia) after genome scanning of 33 332 patients and 27 888 controls in the largest ever genetic study of psychiatric illness. Specifically, variation in calcium-channel activity seemed to be of importance.